Alzheimer's disease (AD) is the most common type of dementia characterized by a progressive decline in cognitive function in particular the memory domain 3
Since then, many medical professionals have investigated the potential beneficial effects of statins on long-term cognition and decreased incidence of cognitive related disease
Atorvastatin oral tablet dosage and frequency will depend upon several factors, the most important being the medical condition it is being targeted for and Adjusted RRs per 1-SD increase in LDL cholesterol in people younger than 65 years at baseline (n=636 262) were 1·10 (95% 1·04-1·15) for dementia diagnosed in the first 10 years after measurement and 1·17 (1·08-1·27) for dementia diagnosed more than 10 years after measurement
5-year follow-up of 18,846 people taking statins, the medication had no link with dementia or changes in cognitive Statins are associated with decreased incidence of Alzheimer's disease, dementia, Parkinson's disease, multiple sclerosis, and amyotrophic lateral sclerosis
rosuvastatin fluvastatin They also examined their risk for three types of dementia — Alzheimer's disease, vascular dementia, and unspecified dementia
1 The prevalence of AD is expected to increase 40% by 2025, reflecting the growth of an aging group of baby boomers and the expanding proportion of the population age >65 years
Their antioxidant and anti-inflammatory effects seem to promote cardiovascular and cerebrovascular health, and might confer neuroprotection through other mechanisms
1, 2 In past decades, cholesterol is implicated as one of several vascular risk factors for dementia by alters the degradation of the amyloid precursor protein, which plays a Aims: As the potential impact of statins on cognitive decline and dementia is still debated, we conducted a meta-analysis of observational studies to examine the effect of statin use on the risk of Alzheimer's disease (AD) and dementia
The risk of very serious side effects is extremely low
A study published in the American Journal of Cardiology casts serious doubts on the commonly held belief that lowering your LDL-cholesterol, the so-called bad cholesterol, is the most effective way to reduced arterial plaque
insomnia (trouble sleeping) muscle pain or weakness*
Watch: The Mayo Clinic Minute Journalists: Broadcast-quality video pkg (1:00) is […] Serious side effects of Lipitor that have been reported include: irregular results of liver function tests, which could be a sign of liver damage
Middle-aged: persons up Baseline neurocognitive ability was an effect modifier for the associations of statins with dementia (p for interaction < 0
These findings await The new study, published Wednesday in Neurology, found that having either high or low levels of high-density lipoprotein, or HDL, cholesterol, may increase the risk of dementia in older adults
"Vascular dementia is caused by blockages in small blood Lipitor can cause side effects, also called adverse effects, that range from mild to serious
In that group, 24% of lipophilic statin users developed dementia over the next eight years, versus 10% of people not using any statin and 11% of hydrophilic statin users
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There was no sex difference in the risk reduction, the results were similar for lipophilic Joint pain
A 2010 meta-review of medical trials involving over 65,000 people concluded that Statins decreased the risk of dementia, Alzheimer's disease, and even improved cognitive impairment in some cases
The relationship between lipid levels and the development of dementia is an evolving but confusing landscape
27%) have dementia
The use of potent statins (atorvastatin, rosuvastatin) was associated with a lower risk of dementia than the use of less potent statins
These drugs may help stabilize the plaques on blood vessel walls and Statin Side Effects
Patients with mild cognitive impairment or normal cognition who used lipophilic statins were found to have more than double the risk of developing dementia compared to statin non-users
99 per year
However, they noted that the findings were part of an observational The relationship between statins and dementia is complex
"This is the first time we've The typical dosage range of Lipitor is 10 mg to 80 mg once per day
Recently, Barthold et al
Researchers scrutinized health records of more than 11 million people who saw their primary care doctors from 1987 to 2013
Some people taking statins report side effects, including memory loss
104 Citations 66 Altmetric Metrics Abstract We conducted a systematic review and meta-analysis to investigate whether the use of
Baseline neurocognitive ability was an effect modifier for the associations of statins with dementia (p for interaction < 0
Although high total cholesterol (TC) in late life has been suggested as protective against dementia 10, and a weaker association between LDL-C level and
That led to the conclusion that, among patients with early mild cognitive impairment and low-to-moderate serum cholesterol levels at baseline, patients
A long-term care benefit, for example, could become a more common route of insured care in some dementia cases
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